EBC-129 for advanced solid tumors with limited treatment options
Treatments studied
Part of Cancer clinical trials.
This Phase 1 study tests EBC-129, a new investigational treatment, in people with advanced solid tumors that cannot be fully removed and have limited or no good standard treatment options. The goal is to learn if the treatment is safe, find helpful dosing, and see signs it may slow the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult (≥18 years in the US, or ≥21 years in Singapore)
- Your body weight is between about 40 kg and 100 kg at first, and up to 120 kg later in the study
- Your solid tumor is advanced and cannot be removed, and standard treatments either don’t work, aren’t tolerated, or don’t have proven benefit
- Your health and daily functioning are fairly good (performance status 0–2, depending on the study part)
- You can provide blood and organ tests showing enough liver, kidney, and bone marrow function
- You can provide a tumor tissue sample (from an existing sample or a new biopsy), unless your doctor decides biopsy isn’t safe for you
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early study tests a new medicine (BPI-460372) in adults with advanced solid cancers that have come back or can’t be treated with standard options. It may help by targeting specific cancer changes in certain tumors, and doctors will also learn the safest dose.
This study tests a new investigational drug called BI 3968621, given either by itself or with another drug called ezabenlimab, for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to find safe and effective doses and see if the combination helps shrink tumors or slow their growth.
This Phase 1 trial tests how different doses of a study drug (BI 1703880) work and how safe they are when given with ezabenlimab for advanced solid tumors. It’s for people whose cancer can’t be removed with surgery and who have tried standard treatments or can’t get them.
This trial tests a new investigational drug, BMS-986488, alone or with another drug (adagrasib), for people with advanced solid tumors that have not responded to other treatments. It aims to see if the drug is safe and works against certain cancers.
This trial tests an experimental drug (TEV‑56278) alone or with another drug (pembrolizumab) for people with advanced solid tumors that have not responded to standard treatments. The goal is to find a safe dose and see if it helps shrink tumors.
This trial tests a new drug called EVM14, alone or with other treatments, for people with advanced solid tumors that can't be removed by surgery or have spread. It aims to see if the drug is safe and helps shrink or control the cancer.
Hear when a new Advanced Solid Tumours trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.