Comparing statins and ezetimibe for heart patients with metabolic syndrome
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial tests if pitavastatin alone or with ezetimibe affects blood sugar differently than atorvastatin in people who have heart or blood vessel disease and metabolic syndrome but do not have diabetes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with high cholesterol or other blood fat problems
- You have a history of heart attack, stroke, or other blood vessel blockages
- You have metabolic syndrome (conditions like high blood pressure, belly fat, or high blood sugar) but do not have diabetes
- Your heart or blood vessel event happened more than one year ago
- You are not allergic to statins or ezetimibe, and you have not had side effects from statins before
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study watches how well a combination cholesterol medication (pitavastatin and ezetimibe) works in people who have high cholesterol and metabolic syndrome (a cluster of health issues including high blood pressure, blood sugar, and cholesterol). You'll be monitored over time to see if the medication helps and is safe for you.
This trial tests a combination pill of two cholesterol-lowering medicines (pitavastatin and ezetimibe) in adults who have been taking either atorvastatin or rosuvastatin for at least 3 months. It aims to see if switching to this new combination is safe and effective.
This trial studies whether high-intensity statin plus ezetimibe can improve heart health in people who do not have symptoms but have calcium buildup in their heart arteries. It may help lower cholesterol and reduce future heart risks for the right participants.
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
This trial tests a medicine called Ezefeno to see if it helps lower cholesterol in people with type 2 diabetes who are already on statins. It may be an option if you have high triglycerides and other heart risk factors.
This study compares two different ways of lowering cholesterol: a moderate statin (pitavastatin) plus another drug (ezetimibe) versus a stronger statin alone. The goal is to see which approach is safer regarding the risk of developing new diabetes.
Hear when a new Atherosclerotic Cardiovascular Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.