Kidney artery treatment for heart failure with normal heart pumping
Part of Heart & circulation, Kidney & urinary clinical trials.
This study tests whether renal denervation (a procedure to reduce overactive signals in kidney arteries) can help people who have heart failure but keep a normal pumping ability and still have high blood pressure. It aims to improve blood-pressure control and heart function in this specific group.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have ongoing signs or symptoms of heart failure (you feel short of breath, tired, or have swelling).
- Your heart’s pumping strength is preserved, meaning ejection fraction is 50% or higher.
- Your doctor has evidence your heart has trouble relaxing (diastolic dysfunction).
- You have high blood pressure (systolic > 140 and/or diastolic > 90) and are already on at least 2 blood-pressure medicines for at least 6 months with stable doses.
- Your blood pressure is reasonably controlled on a 24-hour monitor (less than 140/90).
- Your kidneys are strong enough (eGFR 30 or higher) and your body’s blood-vessel anatomy allows the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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