Magnesium to help protect kidneys during high-risk chest surgery
Treatments studied
Part of Cancer clinical trials.
This Phase 2 trial studies whether giving magnesium by IV can help prevent sudden kidney injury around the time of certain major chest (thoracic) cancer surgeries. If you qualify, you may receive magnesium or a comparison treatment to see if kidney protection improves after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 18 or older and having surgery for malignant mesothelioma with a specific BWH thoracic surgeon using HIOC.
- Your kidney function is not too low (eGFR is 45 or higher) and you’re not on dialysis/renal replacement therapy.
- Your magnesium level is not too high (serum magnesium must be 3 mg/dL or less) before surgery.
- You are not pregnant or breastfeeding.
- You do not have certain heart rhythm/conduction or heart disease history (like major coronary artery disease, very slow heart rate, or certain AV blocks without a pacemaker).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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