Sirolimus for active IgG4-related disease
Treatments studied
Part of Immune system & allergy clinical trials.
This trial tests a drug called sirolimus (which helps calm the immune system) for people with active IgG4-related disease. It may help reduce symptoms like swelling and pain if your current treatments are not working well.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of IgG4-related disease (IgG4-RD), a condition where your immune system causes swelling in different parts of the body.
- Your disease must be active, meaning it is causing symptoms that need treatment.
- In the last 3 months, you must not have taken high-dose steroids (more than 10 mg of prednisone a day), immune-suppressing drugs, or biologic treatments.
- You must not have other serious health problems like active infections (hepatitis B or C, tuberculosis), cancer within the last 5 years, or unstable heart, lung, kidney, liver, or mental health conditions.
- If you are a woman who can have children, you must not be pregnant, planning pregnancy, or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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