Clin2
NCT05772481Possibly a fitRecruiting

PET-MRI scan test for rectal cancer after pre-surgery treatment

Rectal Cancer

Part of Cancer, Digestive system clinical trials.

This study looks at whether a special scan called PET-MRI can better show how rectal cancer responds to treatment given before surgery. If it works well, it could help doctors plan the right next steps after chemoradiotherapy.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
18 years to 75 years
Study type
Observational

Who can take part

  • You have confirmed rectal cancer based on biopsy results
  • Your cancer is locally advanced (for example, cT3–cT4) with no spread to distant organs
  • Your medical team plans for you to have pre-surgery chemotherapy and chemoradiotherapy, then surgery if possible
  • You are well enough for treatment (performance status ECOG 0 to 2)
  • You can safely have MRI and PET scan, and the study medicines (including chemo drugs like 5-FU, oxaliplatin, or irinotecan)
  • If you can become pregnant: you agree to effective birth control and have a negative pregnancy test

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06057831Not yet recruiting· Phase 2
PET/MRI scans for rectal cancer

This study uses PET/MRI scans to look at rectal cancer in detail. It may help doctors plan treatment more accurately. The study is for people with stage 2-3 rectal cancer who will get chemotherapy and radiation before surgery.

NCT06719414Recruiting
Using a special MRI to predict rectal cancer response to pre-surgery therapy

This trial uses a special type of MRI scan (called amide proton transfer-weighted imaging) to look at your rectal cancer before and after chemotherapy and/or radiation. The goal is to see if the scan can predict whether the cancer has completely disappeared by the time of surgery, which could help guide future treatment decisions.

Guangzhou, Guangdong
NCT02704520Recruiting
MRI scoring test for rectal cancer response to treatment

This study looks at how an MRI “score” (mrTRG) matches how well locally advanced rectal cancer shrinks after pre-surgery chemotherapy and radiation. The goal is to use MRI results to better predict treatment response and guide care.

Aberdeen, Aberdeenshire
NCT07404228Not yet recruiting
Using MRI to predict rectal cancer response to pre-surgery treatment

This study uses MRI scans to try to predict whether your rectal cancer completely disappears after pre-surgery chemoradiotherapy. The goal is to better personalize treatment decisions, possibly helping some patients avoid surgery.

Montpellier, Herault
NCT07552207Not yet recruiting
Comparing two PET scans for rectal cancer lymph node staging

This trial compares two imaging techniques, a new type of PET/MRI with a special tracer called FAPI versus a standard tracer called FDG, to see which is better at detecting spread of rectal cancer to nearby lymph nodes. The results may help doctors choose the best scan for planning your surgery.

NCT04103372Recruiting
MRI check for early rectal cancer or large polyps

This trial uses a special MRI before treatment to better understand early rectal cancer or suspicious large polyps. It may help doctors choose care that avoids bigger surgery when possible.

Reading, Berkshire

Hear when a new Rectal Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.