Study of a new medicine for anemia, first tested for safety
Part of Blood & lymphatic clinical trials.
This Phase 1 trial tests how safe APG-5918 is, how the body processes it, and looks for early signs it may help people with certain types of anemia. It may include healthy volunteers and people with anemia, but the study is very selective to protect participants.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18–55 years old if you are a healthy volunteer (healthy-volunteer group only).
- If you have anemia: hemoglobin (Hb) must be 100 g/L or lower on screening, and you must weigh at least 40 kg.
- Have normal iron status (healthy volunteers) OR for anemia: folate and vitamin B12 must be within the normal range.
- Have acceptable blood test results for liver health (ALT/AST and bilirubin) and no ongoing serious bleeding.
- Have no major heart/kidney problems, no active infection, and no recent major treatments that could interfere (like IV iron or certain medicines in the past month).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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