Clin2
NCT05776472Possibly a fitRecruiting

Study real-world pegcetacoplan effects in adults with PNH

Paroxysmal Nocturnal Hemoglobinuria

Treatments studied

Part of Blood & lymphatic clinical trials.

This study looks at how the medicine pegcetacoplan works in real life for adults with paroxysmal nocturnal hemoglobinuria (PNH). It may help doctors understand expected benefits and everyday use patterns.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
200 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You must be at least 18 years old and have a confirmed PNH diagnosis.
  • You started taking pegcetacoplan for PNH within the last 12 months, or it has been prescribed for you at enrollment.
  • Your decision to start pegcetacoplan is made by your treating doctor as part of routine care, not because of this study.
  • You must be able and willing to sign written consent to join the study.
  • You likely cannot join if you joined another drug study that involves treatment within the past 3 months.
  • You also likely cannot join if your current pegcetacoplan treatment started as part of an interventional (treatment) study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06931691Recruiting
Study of Iptacopan for adults with PNH in China

This study looks at how well iptacopan works for people with PNH (a condition where red blood cells break down too quickly). It is for adults who have never used certain treatments or who have been on other similar medicines.

Hefei, Anhui
NCT06932471Recruiting· Phase 3
Study of a new drug for PNH patients with anemia despite current treatment

This trial tests a new pill (MY008211A) for people with paroxysmal nocturnal hemoglobinuria (PNH) who still have low red blood cell counts (anemia) even after taking anti-C5 antibody therapy. The goal is to see if this new drug can raise hemoglobin levels and improve energy.

Beijing, Beijing Municipality
NCT06745622Recruiting· Phase 2
Long-term safety of HSK39297 for PNH patients

This study is for people with paroxysmal nocturnal hemoglobinuria (PNH) who have already taken the experimental drug HSK39297. It checks the long-term safety of continuing the treatment and makes sure it is still helpful.

Nanjing, Jiangsu
NCT05646524Not yet recruiting· Phase 2
NM8074 for adults with PNH not yet on complement inhibitors

This Phase 2 study tests how well and how safely NM8074 works for adults with paroxysmal nocturnal hemoglobinuria (PNH) who have not recently received a similar “complement inhibitor” medicine. It may help reduce PNH-related blood cell breakdown and anemia, and it will closely monitor side effects.

NCT07416162Recruiting
Study of iptacopan for PNH or C3G in Korea

This trial tests a medicine called iptacopan for people with paroxysmal nocturnal hemoglobinuria (a rare blood disorder) or C3 glomerulopathy (a kidney disease). It aims to see if the drug is safe and effective for Korean patients.

Jeollanam
NCT07470762Recruiting· Phase 1/Phase 2
Study of HS-10542 for paroxysmal nocturnal hemoglobinuria (PNH)

This trial tests a new drug, HS-10542, for people with PNH who are already on a C5 inhibitor like eculizumab or covalizumab but still have low hemoglobin or need transfusions. It aims to see if this additional treatment can improve blood counts and reduce transfusion needs.

Hangzhou, Zhejiang

Hear when a new Paroxysmal Nocturnal Hemoglobinuria trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.