Stent without polymer plus aspirin-like therapy for heart attack
Part of Heart & circulation clinical trials.
This trial studies whether a specific stent (with no polymer coating) plus a single blood thinner plan with aspirin and another P2Y12 medicine is as safe and effective as the standard two-medicine plan after a STEMI heart attack. It may help people avoid longer exposure to stronger blood-thinning if the new approach works as well.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You had a STEMI heart attack and received emergency opening of the blocked artery (primary PCI) successfully.
- Before or by the time of the procedure, you were taking aspirin plus one P2Y12 medicine (ticagrelor, prasugrel, or clopidogrel).
- The heart procedure used a specific polymer-free sirolimus-coated stent and your remaining blockage was small (less than 20–30%).
- You can sign consent and reliably take the study medicines for at least 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares a new type of “drug-eluting” stent (a tiny scaffold that slowly releases medicine) and a single blood-thinner plan versus the usual two-drug blood thinner plan after stent placement in the left main coronary artery. It aims to see if the simpler plan can work while keeping the stent safe.
This study tests whether taking a single blood-thinning medication (instead of two) after heart stent placement is safe and effective over the long term. If you've recovered well from a stent procedure, this trial may help determine the safest way to prevent future heart problems.
This trial tests if a shorter, lower dose of two blood thinners is safe and effective for patients with a recent heart attack or unstable angina who are at high risk for bleeding. It uses a special stent that might allow for less medication.
This trial compares two ways of using anti-platelet (blood-thinner) medicines after a specific kind of heart attack (STEMI) treated with a stent. It aims to see if switching sooner to one medicine (instead of two for longer) works just as well and may reduce risks.
This trial tests whether patients who have had a heart attack or unstable angina and a stent placed with ultrasound guidance can safely stop one of their blood-thinning medicines early. It helps doctors find the best way to prevent future heart problems with fewer side effects.
This trial tests whether a low-dose clot-busting medicine placed into the heart artery after a primary stent can improve outcomes in people with a certain type of heart attack. It also involves short hospital follow-ups and a heart MRI to look at how the heart is recovering.
Hear when a new ST Elevation Myocardial Infarction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.