Clin2
NCT03998319Possibly a fitRecruiting

Testing low-dose clot-busting drug after heart attack stent

STEMIElevated IMR (>32)

Treatments studied

Part of Heart & circulation clinical trials.

This trial tests whether a low-dose clot-busting medicine placed into the heart artery after a primary stent can improve outcomes in people with a certain type of heart attack. It also involves short hospital follow-ups and a heart MRI to look at how the heart is recovering.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
445 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You’re over 18 and your STEMI heart attack started within the last 6 hours
  • Your symptoms lasted at least 20 minutes and your ECG confirmed STEMI
  • You can understand the consent form and sign it, and you can attend all visits/tests
  • When you get your stent during the procedure, it must be a metal drug-eluting stent
  • You agree to have a heart MRI shortly after discharge (3–7 days) and again at 6 months
  • You should have primary PCI (a stent procedure) done—this study is not for people who don’t get it

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07875179Not yet recruiting· Phase 4
Low-dose clot-busting medicine with emergency angioplasty for heart attacks

This trial tests whether adding a low dose of a clot-busting medicine to the standard emergency procedure to open blocked heart arteries can improve outcomes for people having a heart attack. It aims to see if the combination is safe and more effective than the standard procedure alone.

Xuzhou, Jiangsu
NCT05785897Recruiting
Stent without polymer plus aspirin-like therapy for heart attack

This trial studies whether a specific stent (with no polymer coating) plus a single blood thinner plan with aspirin and another P2Y12 medicine is as safe and effective as the standard two-medicine plan after a STEMI heart attack. It may help people avoid longer exposure to stronger blood-thinning if the new approach works as well.

Geneva, Canton of Geneva
NCT06935383Not yet recruiting· Phase 2
Treatment for blocked heart artery and small blood vessel damage after heart attack

This trial tests a new way to treat heart attacks by using a special balloon to deliver medication to the heart's small blood vessels during a standard stenting procedure. It may help reduce damage to the heart muscle after a heart attack.

NCT07641231Not yet recruiting· Phase 4
Heart attack treatment when emergency procedure is delayed

This study tests different ways of restoring blood flow for people having a heart attack (STEMI) when the usual emergency procedure (primary PCI) may be delayed. It aims to see if giving a clot-busting medicine beforehand is as good as waiting for the procedure, or if another approach works better.

Moscow, Select A State
NCT04995159Not yet recruiting
Optimized blood thinner therapy after heart stent placement

This trial tests different blood thinner medicines after a heart stent is placed. It aims to find the best way to prevent blood clots while reducing bleeding risk.

Bengbu, Anhui
NCT04775914Recruiting
Test a heart procedure guide during emergency STEMI treatment

This trial studies whether adding a special heart “reset” step (ischemic postconditioning) and using an imaging guide during the emergency procedure can improve outcomes for people having a STEMI heart attack. It’s meant to optimize treatment when a blocked heart artery is being opened.

Copenhagen, Capital Region

Hear when a new STEMI trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.