Clin2
NCT05806385Possibly a fitNot yet recruiting

Freezing tumors with immune-boosting drugs for early breast cancer

Triple Negative Breast Cancer

Part of Cancer, Skin clinical trials.

This study tests a treatment that combines freezing the tumor (cryoablation) with a medication to boost your immune system to fight the cancer. It is for people with early-stage triple-negative breast cancer, a type that can be harder to treat.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
36 people
Ages
18 years to 90 years
Study type
Interventional

Who can take part

  • You are female and are between 18 and 90 years old.
  • You have been diagnosed with stage I or II breast cancer that is triple negative (meaning it does not have estrogen, progesterone, or HER2 receptors).
  • The cancer must be a single tumor that can be seen on an ultrasound.
  • You have not been treated with radiation, immunotherapy, or an experimental drug before, and you have not been vaccinated recently.
  • You do not have another cancer, inflammatory breast cancer, an autoimmune disease, or a weakened immune system, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06246968Recruiting· Phase 1
Pembrolizumab plus tumor ablation for advanced triple-negative breast cancer

This study tests combining an immunotherapy drug (pembrolizumab, also called Keytruda) with a procedure that freezes or destroys cancer cells directly (called ablation). The goal is to see if this combination can help control triple-negative breast cancer that has spread or is inoperable.

Basking Ridge, New Jersey
NCT06318897Recruiting· Phase 2
Immunotherapy with chemo for early triple-negative breast cancer

This trial tests a combination of an immunotherapy drug (pembrolizumab) plus two chemotherapy drugs (carboplatin and paclitaxel) given before surgery for people with early-stage, triple-negative breast cancer. The goal is to see if this treatment helps shrink or eliminate the tumor before it's removed.

Houston, Texas
NCT06407310Not yet recruiting· Phase 2
Immunotherapy and chemotherapy before surgery for early triple-negative breast cancer

This trial tests whether giving pembrolizumab (an immunotherapy drug) together with chemotherapy before surgery can help treat early-stage triple-negative breast cancer. It aims to improve outcomes by shrinking the tumor before removal.

NCT07629206Recruiting
Freezing therapy for small, early-stage breast cancer

This study tests whether freezing a small breast tumor (cryoablation) is a safe and effective treatment option for older adults with early-stage, hormone-receptor-positive breast cancer. Instead of surgery, the goal is to destroy the tumor by freezing it in place.

Glendale, California
NCT07775014Not yet recruiting
Freezing breast cancer with a needle

This study is testing a treatment called cryoablation, which uses extreme cold to freeze and destroy cancer cells. It is a less invasive option than surgery, so it may be helpful for women who cannot have or do not want conventional breast surgery.

Torino, TO
NCT07398118Not yet recruiting
Freezing treatment for early-stage breast cancer in older adults

This study tests a freezing treatment called cryoablation for early-stage breast cancer in people aged 70 and older. It aims to see if freezing the tumor can be a safe and effective alternative to surgery for those who may be older or frail.

Arnhem, Gelderland

Hear when a new Triple Negative Breast Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.