Trial testing moderate exercise in teens with Marfan syndrome
Treatments studied
Part of Bones, joints & muscles, Genetic & congenital, Heart & circulation, Skin clinical trials.
This trial studies whether doing moderate exercise is safe and helpful for people with Marfan syndrome. It aims to see how exercise affects heart and health measures, like how the aorta and body respond over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Marfan syndrome based on Ghent criteria and genetic eye/ligament findings (often a FBN1 gene change or eye lens displacement).
- You’re between 10 and 25 years old when you join.
- You have NOT had surgery on your aorta (for example, repair of the main heart artery).
- You have NOT had spinal surgery that left implanted materials that could interfere with MRI scans.
- You can safely do moderate exercise; your health conditions must not make exercise too hard.
- Your aorta is not enlarged to the surgery-prevention size (not 4.5 cm or more in diameter).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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