Early circulation-focused care during kidney dialysis in ICU
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial looks at whether starting dialysis-related care early, aimed at improving blood flow to tissues, can help people in the ICU who have sudden kidney failure. It may help reduce problems related to poor tissue circulation, but it is very specific about ICU illness and current treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are in the ICU with sudden kidney injury treated with continuous kidney dialysis (CRRT) for less than 7 days
- You also had at least one other major organ problem in the ICU (such as breathing support/ventilation, needing oxygen, large fluid needs, or using blood-pressure medicines for more than 12 hours)
- Your recent weight loss or ultrafiltration (fluid removal) history fits the study limits (very little weight loss, or total fluid removed under 2000 mL)
- Your blood-pressure medicine dose is low (norepinephrine under 0.5 micrograms/kg/min)
- You do NOT show signs of poor circulation (you would avoid having 2 or more of: slow finger refill, pale/mottled skin, high lactate, or low ScvO2)
- You may qualify if you are not “too overloaded” with fluid (fluid excess under 5% of baseline weight and no clear deep swelling of the lower back/flanks)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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