Clin2
NCT05819853Possibly a fitRecruiting

Semaglutide to help restart periods in PCOS

PCOS (Polycystic Ovary Syndrome) of Bilateral OvariesObese

Treatments studied

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This Phase 3 study tests whether semaglutide can help people with polycystic ovary syndrome (PCOS) start ovulating and having more regular periods. You may join with or without metformin, and contraception rules are important because the medicine must not be used during pregnancy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
80 people
Ages
12 years to 35 years
Study type
Interventional

Who can take part

  • You are assigned female and are between ages 12 and 35
  • You have PCOS with infrequent or absent periods (or no periods after starting menstruation) and blood or physical signs of high androgen levels
  • You have low activity (less than 2 hours per week of moderate exercise)
  • Your weight fits the study ranges for your age, and your weight has stayed within about 5 kg for the last 3 months
  • You can use reliable non-hormonal birth control during the study (like a copper IUD) and avoid pregnancy
  • You cannot have certain health problems or medicines that affect insulin, thyroid, or the stomach/intestines (details below)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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