Methylene blue given during leg amputation surgery
Treatments studied
Part of Pain clinical trials.
This trial studies whether infusing methylene blue during above- or below-knee leg amputation can improve outcomes for people with poor blood flow to the legs. It targets patients having surgery under general anesthesia, while excluding those with certain allergies or blood clotting problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have poor blood flow in one or both lower legs from a vascular problem
- You are scheduled for an above-knee or below-knee amputation
- Your surgery will be done under general anesthesia (you are fully asleep)
- You do not have a history of allergy to local anesthetics
- You do not have a history of allergy to methylene blue
- You are not taking blood thinners (anticoagulants) and you do not have a clotting disorder
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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