Clin2
NCT07276867Possibly a fitRecruiting

Spinal Add-On Medicine for Leg Amputation from Sarcoma

IntrathecalDexmedetomidineFentanylBupivacaineSpinal AnesthesiaAbove Knee AmputationSarcomasLower Extremity

Treatments studied

Part of Cancer clinical trials.

This trial tests adding two medicines (dexmedetomidine and fentanyl) versus fentanyl alone to the standard spinal anesthetic for above-knee amputation surgery for lower limb sarcoma. The goal is to see if the combination provides better pain control during and after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
58 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You are between 18 and 60 years old.
  • You are scheduled for an above-knee leg amputation because of sarcoma (a type of cancer).
  • Your height is between about 4'11" (150 cm) and 6'1" (185 cm).
  • Your body mass index (BMI) is between 18 and 35.
  • You do not have serious heart problems, allergies to the study drugs, or conditions that prevent spinal anesthesia.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07640516Recruiting
Pain Relief Comparison for Amputation Surgery in High-Risk Patients

This study compares two medications (dexmedetomidine and fentanyl) mixed with a numbing agent to see which works better for blocking pain during above-knee amputation surgery in patients with serious heart or lung disease. Both drugs are already used in anesthesia, and this trial tests which combination is safest and most effective for you.

Cairo
NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery

This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.

Cairo
NCT06662175Not yet recruiting· Phase 2/Phase 3
Adding a medication to spinal anesthesia for leg surgery

This study tests whether adding a medication called dexmedetomidine to spinal anesthesia can make pain relief last longer and work better. This could help reduce pain after your leg or foot surgery.

Peshawar, KPK
NCT07117565Not yet recruiting· Phase 4
Adding sedation drugs to spinal block to prevent urine retention after leg surgery

This trial tests whether adding dexmedetomidine or fentanyl to the standard spinal anesthesia medication helps prevent trouble urinating after leg surgery. If you qualify, you'll get one of these added to your spinal block, and the study will watch how your bladder function recovers.

Bhadrapur, Koshi
NCT06685705Not yet recruiting· Phase 4
Comparing pain relief add-ons for lower abdominal surgery

This study tests whether adding magnesium, neostigmine, or fentanyl to the standard spinal anesthetic improves pain relief after lower abdominal surgery. Participants will receive one of these add-ons to see which works best.

NCT07525999Not yet recruiting· Phase 4
Drug combination to reduce long-term pain after spine surgery

This study tests whether combining two medicines, dexmedetomidine and esketamine, during spine surgery can help prevent chronic pain that sometimes continues for months after surgery. If you are having spine surgery and will use a pain pump afterward, this trial might be a good fit for you.

Beijing, Beijing Municipality

Hear when a new Dexmedetomidine trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.