Liver cirrhosis network rosuvastatin trial
Treatments studied
Part of Digestive system clinical trials.
This study tests whether the drug rosuvastatin, a cholesterol-lowering medicine, can improve liver health in people with cirrhosis. If you have compensated cirrhosis (no recent serious liver problems), you might be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 75 years old.
- Your cirrhosis is caused by fatty liver disease, alcohol, or untreated/treated hepatitis B or C.
- You have cirrhosis that is stable (compensated), meaning no serious symptoms like fluid buildup, confusion, or bleeding in the past year.
- You have taken two liver stiffness measurements (FibroScan) at least 2 hours and up to 60 days apart, with both reading at least 15 kPa and not over 50 kPa.
- You have not been on a statin (like atorvastatin or rosuvastatin) in the last 6 months, and you have no need for a statin based on your heart health history or very high cholesterol.
- You do not have any other liver disease cause (like autoimmune or certain genetic conditions), and you have not had certain stomach surgeries or transplants.
- You are not currently using certain medications, and you do not have recent kidney failure, very low blood counts, or poorly controlled diabetes.
- You are willing to stop taking any excluded medications and can comply with the study schedule.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether atorvastatin (a cholesterol medicine) can lower the chance of liver cancer (HCC) in people with advanced liver scarring or cirrhosis. Participants are compared to placebo (inactive pill) while researchers track safety and cancer risk.
This trial tests whether adding a statin (simvastatin) to the usual heart medication carvedilol helps people with both cirrhosis and a related heart problem live longer and avoid serious liver complications.
This study looks at how nutrition affects the health of people with liver cirrhosis (scarred liver) and aims to build a tool to predict their outcomes. If you have cirrhosis, joining may help researchers find better ways to support your health.
This trial tests if adding a statin to beta blocker treatment helps people with advanced liver disease (cirrhosis) who have had complications like fluid buildup, confusion, or bleeding. It is for patients who are already taking a non-selective beta blocker and will be followed for 12 months.
This study follows people with cirrhosis to see how best to detect liver cancer early. If you qualify, you may receive regular monitoring that could help find liver cancer sooner, when treatment is more likely to work.
This trial tests if metformin can lower the pressure in the liver's blood vessels (portal hypertension) in people with cirrhosis. The goal is to see if it can help reduce complications like swelling or bleeding.
Hear when a new Cirrhosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.