Ondansetron before heart ablation for atrial fibrillation
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 to 100 years old.
- You have ECG-confirmed atrial fibrillation and/or atrial flutter and you’re planning an elective catheter ablation.
- You’re on recommended blood thinners for atrial fibrillation (or your stroke-risk score is very low and your doctor can omit anticoagulation).
- If you could become pregnant, you must not be a woman of childbearing potential.
- In the past 6 months, you have not had fainting (syncope) of unknown cause.
- You do not have certain heart electrical/medical issues (for example: very low heart pumping strength, very low ejection fraction, specific long-QT conditions, or history of dangerous rhythm problems).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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