Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 550 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07792239RecruitingPhase 2
Study of budiodarone for atrial fibrillation
This study tests a new medicine, budiodarone, to help control atrial fibrillation (an irregular heartbeat) in people who haven't been helped by other treatments. It may reduce the time spent in AF and improve symptoms.
GdyniaAges 18–80 - NCT07575269Recruiting
New ablation treatment for irregular heartbeat
This trial tests a new tool called FARAFLEX that uses pulsed electrical energy to treat atrial fibrillation (an irregular heart rhythm). The goal is to see if this method can safely stop AF symptoms in people whose medications haven't worked.
Jonesboro, ArkansasAges 18 years+ - NCT07626411RecruitingPhase 3
Blood Thinner Study for Irregular Heartbeat
This study tests a new blood thinner to prevent strokes and blood clots in people with atrial fibrillation (a common heart rhythm problem). You may qualify if you have atrial fibrillation and at least one risk factor for stroke, or if you've never taken a blood thinner before.
Dothan, AlabamaAges 18 years+ - NCT07324772Recruiting
Exercise program to improve symptoms in atrial fibrillation and heart failure
This study tests if starting a supervised exercise program can help older adults with both atrial fibrillation and a type of heart failure called HFpEF feel better and have a better quality of life. You'll be asked to join exercise sessions and have regular check-ins to see how you're doing.
Chicago, IllinoisAges 60–99 - NCT06938412Recruiting
Exercise and Fitbit for Afib patients
This study tests whether using a Fitbit activity tracker and a supportive exercise program helps people with AFib become more active. It may help you feel better and manage your heart rhythm.
New York, New YorkAges 18 years+ - NCT07621003Recruiting
PULSed Field Ablation for New-Onset Atrial Fibrillation
This study tests a newer ablation technique using pulsed electrical energy to treat atrial fibrillation (an irregular heartbeat). You may qualify if you were recently diagnosed with AF and haven't had ablation before.
Bad OeynhausenAges 18 years+ - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+ - NCT07757282Recruiting
Blood lipid (fat) levels in atrial fibrillation
This study looks at fats (lipids) in the blood of people with atrial fibrillation (an irregular heartbeat) compared to people with other heart conditions but no atrial fibrillation. The goal is to find patterns that may help understand the condition better and improve diagnosis or treatment.
Xi'an, ShaanxiAges 18 years+ - NCT06523738Recruiting
Studying heart size changes after shock and ablation for AF
This trial looks at how the size of your heart's upper-left chamber (left atrium) changes after a procedure to restore a normal rhythm (cardioversion). It aims to see if these changes can predict whether atrial fibrillation (AF) will come back after a later procedure called radiofrequency ablation.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06061978Recruiting
Pacing after a heart procedure for rapid atrial fibrillation
This trial studies whether a special type of pacing (stimulating the heart's natural electrical system) works better than standard pacing after a procedure to control very fast heart rhythms. It's for people who already have a pacemaker and are getting a specific treatment for atrial fibrillation.
CaenAges 18 years+ - NCT04432220RecruitingPhase 4
Taking blood thinners one year after atrial fibrillation ablation
This study looks at whether people who have stayed in normal rhythm one year after atrial fibrillation ablation should continue blood thinning treatment. It may help guide safer, more personalized choices about long-term blood thinners after a successful procedure.
SeoulAges 19–80 - NCT03868150RecruitingPhase 4
Preventing an abnormal heart rhythm after heart surgery
This trial studies whether giving a medication (amiodarone) during and after certain heart surgeries can help prevent atrial fibrillation, an irregular heartbeat that can happen after surgery. It may help by aiming to stop this rhythm problem before it starts.
Stanford, CaliforniaAges 18 years+ - NCT07741383Recruiting
Combined procedure for severe mitral regurgitation and atrial fibrillation
This study tests whether combining a valve repair procedure with a heart rhythm reset procedure is safe and effective for people with severe mitral regurgitation and atrial fibrillation. It may help improve heart function and reduce symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT07523750Recruiting
Comparing two catheter treatments for persistent atrial fibrillation
This study compares two different catheters that use pulsed field ablation to treat a type of irregular heartbeat called persistent atrial fibrillation. The goal is to see which one works better and is safer.
Phoenix, ArizonaAges 18–80 - NCT07349121Recruiting
Testing the Farapulse and Watchman devices together
This trial is for people who need both a special heart treatment called pulsed field ablation (FARAPULSE) and a device to close off a small pouch in the heart (WATCHMAN FLX Pro or WATCHMAN FLX) to prevent strokes. The study will see how well both procedures work when done together.
AalstAges 18 years+ - NCT07738523RecruitingPhase 2/Phase 3
Caffeine and heart rate control in permanent atrial fibrillation
This trial tests whether stopping caffeine for up to two months helps control heart rate in people with permanent atrial fibrillation. If you drink at least one cup of caffeinated coffee a day, you may be able to join and help find out if giving up caffeine improves your heart rate.
Getafe, MadridAges 18–80 - NCT07217067RecruitingPhase 2
Study of PKN605 for people with atrial fibrillation
This trial tests a new medicine called PKN605 for people with atrial fibrillation (irregular heartbeat). The goal is to see if it can safely help control heart rhythm. You will need to have had at least two AF episodes recently and meet other heart health criteria.
Tupelo, MississippiAges 18 years+ - NCT07734194Recruiting
Studying a new sedation combo for afib treatment
This trial tests a mild sedation method using remimazolam and fentanyl during a procedure called pulsed-field ablation for atrial fibrillation (afib). It aims to find a safe and effective way to keep you comfortable without deep sedation.
PragueAges 18 years+ - NCT07728539Recruiting
Comparing a faster ablation method for atrial fibrillation
This study compares a newer, faster type of ablation (high-power short-duration) with the standard approach for treating atrial fibrillation. The goal is to see which method is safer and more effective at restoring a normal heart rhythm.
MoscowAges 18–70 - NCT07726056Recruiting
Heart ablation in athletes with atrial fibrillation
This trial tests if a heart procedure (cardiac ablation) helps endurance athletes who have atrial fibrillation (an irregular heartbeat) perform better in sports. Athletes will track their training data before and after the procedure to see if their performance improves.
MelbourneAges 18–80 - NCT07724899Recruiting
A new ablation treatment for atrial fibrillation
This study tests a new type of ablation (pulsed field ablation) for people with atrial fibrillation who haven't gotten enough relief from medication alone. It aims to see if isolating the superior vena cava along with the pulmonary veins is safe and effective.
Chengdu, SichuanAges 18 years+ - NCT07713615Recruiting
Blood clots and heart ultrasound in people with device-detected afib
This study looks at blood clotting markers and heart ultrasound in people who have a pacemaker or defibrillator that has detected short episodes of atrial fibrillation (afib). The goal is to better understand stroke risk and help guide future treatment decisions.
EsbjergAges 50 years+ - NCT05511389Recruiting
Testing better electrode placement for heart rhythm shock
This study tests whether two different positions of the electrodes (pads) used for an electrical shock work equally well for people with atrial fibrillation or flutter. It may help improve how safely and effectively the shock restores a normal rhythm.
Hamilton, OntarioAges 18 years+ - NCT02997254Recruiting
Testing computer methods that analyze atrial fibrillation heart signals
This study compares different computer “analysis methods” that look at real-time heart recordings from people with atrial fibrillation. It may help improve how atrial fibrillation is evaluated during/after an ablation procedure.
Stanford, CaliforniaAges 21–90
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Atrial fibrillation trials by city
Studies with a site in or near these metro areas.
Atrial fibrillation trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 550 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.