Clin2
NCT05846789Possibly a fitRecruiting

Tocilizumab plus chemo for metastatic breast cancer

Metastatic Breast CancerTriple Negative Breast CancerEstrogen-receptor-low Breast CancerER Positive, HER2 Negative Breast Cancer

Part of Cancer, Skin clinical trials.

This trial tests whether adding tocilizumab, a drug that calms the immune system, to standard chemotherapy helps control certain advanced breast cancers. It is for people with triple-negative or ER-positive, HER2-negative breast cancer that has spread or come back.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
168 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • 18 years or older
  • Have advanced breast cancer that is triple-negative or ER-positive, HER2-negative
  • If triple-negative, you may have had up to 2 prior treatments for advanced disease
  • If ER-positive, you must have had hormone therapy and a CDK inhibitor, and up to 3 prior chemotherapies
  • You must be able to start standard chemotherapy as planned
  • Have good organ function and be in good daily health (ECOG 0 or 1)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06078384Recruiting· Phase 2
Pembrolizumab and chemo for early-stage triple-negative breast cancer

This trial studies whether adding pembrolizumab (an immunotherapy) to standard chemotherapy after surgery can improve outcomes for people with early-stage triple-negative breast cancer. The treatment you receive depends on the level of immune cells (TILs) found in your tumor.

Amiens
NCT06690840Recruiting· Phase 2
Atezolizumab plus chemo for advanced triple-negative breast cancer

This trial tests atezolizumab (an immunotherapy) plus chemotherapy to activate immune cells in people with triple-negative breast cancer that has spread or cannot be removed. It is for those who have had immunotherapy before during early treatment but not for advanced disease.

Monza, Monza
NCT06202313Not yet recruiting· Phase 2
Immunotherapy plus chemotherapy for metastatic triple-negative breast cancer

This trial tests a new immunotherapy drug (cadonilimab) combined with a chemotherapy (eribulin) against chemotherapy alone for triple-negative breast cancer that has come back or spread. If you receive the combination, the goal is to see if it helps control the cancer better or for longer.

Shenyang, Liaoning
NCT06342037Recruiting· Phase 2
New immunotherapy options for advanced triple-negative breast cancer

This trial tests two immunotherapy drugs (atezolizumab and tiragolumab) for people with advanced triple-negative breast cancer that has not responded to standard treatments. It aims to see if this combination can shrink or slow the cancer.

Amsterdam, North Holland
NCT04501523Recruiting· Phase 2
ctDNA-guided immunotherapy boost after chemotherapy for triple-negative breast cancer

This Phase 2 study checks whether a blood test that looks for cancer DNA (ctDNA) can help decide who should get an extra 12-month immunotherapy treatment after standard chemotherapy and surgery. It may help reduce the chance of the cancer coming back in people with triple-negative breast cancer.

Guandong, Guangdong
NCT04301739Not yet recruiting· Phase 3
Immunotherapy plus chemo for triple-negative breast cancer

This trial tests whether adding an immunotherapy drug (HLX10) to chemotherapy before surgery, and then continuing it after surgery, helps people with triple-negative breast cancer more than chemotherapy alone. It is a type of breast cancer that does not respond to hormone treatments or HER2-targeted treatments.

Hear when a new Metastatic Breast Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.