Checking endothelial cell health before corneal transplant
Part of Eyes & vision clinical trials.
This study tests how well a patient’s corneal lining cells are preserved before corneal transplantation, and uses that to guide the transplant approach. It may help improve transplant planning and outcomes for people who need treatment for conditions like keratoconus or Fuchs endothelial dystrophy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- You are planning a corneal transplant that replaces the cornea’s inner lining cells (PK, DSAEK, UT-DSAEK, or DMEK)
- Your reason for transplant is keratoconus or Fuchs endothelial dystrophy (lower-to-moderate rejection risk)
- You have not had a corneal transplant before
- You do NOT have a current corneal infection (microbial keratitis) or non-infectious/autoimmune keratitis
- You do not have eye conditions that would block the study, like a corneal perforation, active/inflamed uveitis, uncontrolled high eye pressure, planned preloaded DSAEK/DMEK, or an anterior chamber lens
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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