Vitamin and light treatment before risky corneal transplant
Part of Eyes & vision clinical trials.
This trial studies whether pretreatment with a specific vitamin and ultraviolet light can help a future, high-risk corneal transplant keep its new cornea healthy for longer. It may help people whose corneas already have new blood vessels, which can make transplant results harder.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You need a corneal transplant because your cornea has abnormal new blood vessels
- At least two sections of your cornea are covered by these new blood vessels
- You’re willing and able to attend follow-up visits and follow the study plan
- You can give informed consent (you or a legally allowed witness can sign before any study steps)
- Your cornea thickness is not too thin (with specific allowed exceptions for certain areas)
- You do not have certain eye problems like active eye inflammation or an active corneal ulcer
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial uses donated corneal tissue that was treated with a special light and riboflavin (collagen cross-linking) to strengthen it before transplant. The goal is to improve vision in people with severe keratoconus, a condition where the cornea bulges into a cone shape and gets very thin.
This trial tests two different UV light exposure times (18 minutes vs. 24 minutes) during a corneal crosslinking procedure for people with keratoconus or similar corneal thinning conditions. The goal is to see if the shorter time works as well as the longer one.
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