Fecal transplant study for depression
Treatments studied
Part of Digestive system, Mental health clinical trials.
This trial tests whether fecal microbiota transplantation (FMT, a stool-based treatment that changes gut bacteria) can improve symptoms of first-episode depression. It’s mainly for adults with moderate-to-severe depression based on a common symptom score.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old
- You have your first episode of depression diagnosed by ICD-10
- Your depression symptom score (HAMD) is 17 or higher
- You can provide informed consent
- You have not taken antibiotics in the past month
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a fecal microbiota transplant (FMT) can help young adults with irritable bowel syndrome with diarrhea (IBS-D) who also have symptoms of anxiety or depression. FMT involves putting processed stool from a healthy donor into your gut to improve digestive and mental health at the same time.
This trial studies whether fecal microbiota transplantation (a procedure that transfers gut bacteria) can improve symptoms in people with schizophrenia. It may help by changing the gut microbiome, which researchers think could affect brain and behavior symptoms.
This trial tests whether transplanting healthy gut bacteria (fecal microbiota) can help people with depression that does not respond well to the antidepressant escitalopram. You will first take escitalopram for 2 weeks, and if it doesn't help enough, you may receive either the real transplant or a placebo capsule.
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
This study tests whether a treatment called fecal microbiota transplant (FMT) can improve gut health and reduce eating disorder symptoms in young women with anorexia nervosa who have digestive issues.
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
Hear when a new Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.