Tested medicine to prevent depression after hip or leg fractures
Treatments studied
Part of Injuries & trauma, Mental health clinical trials.
This trial studies whether a type of antidepressant medicine (a serotonin–norepinephrine reuptake inhibitor) can prevent depression after a lower-extremity fragility fracture that was treated with surgery. It’s mainly for older adults, and aims to see if starting this medicine early reduces later depression symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 65 or older
- You had a lower-leg or hip fragility fracture and it was treated with surgery
- You do not have multiple serious injuries (polytrauma)
- Your fracture was not caused by cancer or another disease (not a pathological fracture)
- You are not currently taking SSRI or SNRI antidepressant medicines
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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