Study drug combination for metastatic colon cancer with prior treatments
Treatments studied
Part of Cancer, Digestive system clinical trials.
This Phase 2 trial tests a chemotherapy combination (liposomal irinotecan), along with TAS-102 and bevacizumab, in people with metastatic colon cancer. It may help if your tumor has mismatch repair–proficient features and you’ve already tried standard colon cancer drugs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years of age or older
- Be able to do most daily activities (ECOG performance 0–1)
- Have confirmed metastatic or unresectable colon (colorectal) adenocarcinoma
- Your tumor must be mismatch repair proficient (not mismatch repair deficient or MSI-high)
- Have had prior colon cancer treatment including 5-fluorouracil and oxaliplatin, and irinotecan-type therapy; and meet specific prior-treatment rules for certain tumor types
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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