Colchicine vs placebo for acute myocarditis
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether colchicine (a medicine that reduces inflammation) improves outcomes in people with acute myocarditis soon after symptoms start. Half of participants get colchicine and half get a placebo to see which works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your heart symptoms started 28 days or less ago
- Your diagnosis looks like myocarditis, with chest pain, heart failure symptoms, or palpitations
- Blood tests show heart-injury markers (troponin) above the lab’s 99th percentile
- A special heart MRI confirms myocarditis, and blood vessel blockages were ruled out (in many people over age 40)
- You can use effective birth control during treatment and for 1 month after (if able to have a pregnancy)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if corticosteroids (steroids) help people with acute myocarditis, a sudden inflammation of the heart muscle. It aims to improve heart function and reduce symptoms like chest pain or heart failure.
This trial tests whether the drug colchicine can help people with heart muscle inflammation (myocarditis) that also causes abnormal heart rhythms, a weak heart pump, or high stress markers. Colchicine is an anti-inflammatory medicine that might reduce heart damage and improve symptoms.
This trial tests whether a low dose of the anti-inflammatory drug colchicine can help people who have recently had a heart attack or unstable angina. It aims to see if colchicine reduces the risk of future heart problems.
This trial tests if the anti-inflammatory drug colchicine can help people hospitalized with acute heart failure and a weak heart pump. It may benefit those with elevated inflammation markers.
This trial tests if colchicine, an anti-inflammatory medicine, can help people who recently had a heart attack. It looks for markers in your blood to see who might benefit most.
This trial tests if giving colchicine early after a heart attack (when a drug-coated stent is placed) can help reduce complications. It looks at short-term benefits for people with Non-STEMI.
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