Colchicine for heart inflammation with arrhythmias
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the drug colchicine can help people with heart muscle inflammation (myocarditis) that also causes abnormal heart rhythms, a weak heart pump, or high stress markers. Colchicine is an anti-inflammatory medicine that might reduce heart damage and improve symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have inflammation in your heart muscle, confirmed by a heart MRI or PET scan within the last 3 months.
- You have had symptoms for more than 1 month, including at least one of: very frequent extra heartbeats (3,000+ per day), short runs of fast heartbeats, or sustained fast heartbeats; a weaker heart pump (LVEF less than 50% on echo or less than 60% on MRI); or high levels of heart stress markers (NT-proBNP over 1,000 or BNP over 200).
- You are not currently taking colchicine or other immune-suppressing drugs, and you do not have severe kidney or liver disease.
- You are not pregnant or breastfeeding, and you do not have other serious conditions like recent heart attack, blocked arteries, or certain autoimmune diseases.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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