Clin2
NCT05859074Possibly a fitRecruiting

Testing MQ710 injections alone or with pembrolizumab for advanced cancers

Cutaneous Squamous Cell CarcinomaSCC - Squamous Cell CarcinomaBasal Cell CarcinomaBCCBCC - Basal Cell CarcinomaMelanomaMerkel Cell CarcinomaSebaceous Carcinoma

Treatments studied

Part of Cancer, Infections, Skin clinical trials.

This early-phase study tests MQ710, a medicine given by injection into a reachable tumor, to see how well it can control advanced cancers. Some participants also receive pembrolizumab, an immunotherapy, to help the immune system fight the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
56 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You’re 18 or older
  • You have advanced or metastatic cancer that has come back or did not respond to usual treatments, or there is no standard option
  • You have at least 2 spots the team can inject/target (skin, under the skin, or lymph nodes), and they can biopsy one spot
  • You can have a screening biopsy (and, if needed, a surgical biopsy approach) and you agree to it
  • Your general health and organ tests are good enough (blood counts, kidneys, liver, and ability to tolerate treatment)
  • You have had limited recent treatment, and you meet specific timing rules for prior therapies

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04370587Recruiting· Phase 1/Phase 2
Injecting a cancer medicine into tumors plus pembrolizumab

This Phase 1/2 study tests a medicine injected directly into a tumor, alone or with pembrolizumab (an immune-therapy drug given through a vein). It is for people with advanced or metastatic solid cancers that have grown despite standard treatments, aiming to improve tumor control.

Gilbert, Arizona
NCT06500091Not yet recruiting· Phase 2
New drug with chemotherapy for advanced sarcoma and melanoma

This study tests a new drug (TQB2916) combined with chemotherapy or another drug (penpulimab) in people with certain advanced soft tissue sarcomas or melanoma. The goal is to see if this combination can shrink or control the cancer.

Beijing, Beijing Municipality
NCT06188624Recruiting· Phase 1
Study of TQB2922 for advanced cancers

This trial tests a new drug, TQB2922, for people with advanced cancers that have not responded to standard treatments. The goal is to see if it is safe and how it affects the cancer.

Chongqing, Chongqing Municipality
NCT06649656Not yet recruiting· Phase 1
Experimental drug for advanced cancer after other treatments fail

This study tests an experimental drug called TQB2252 for people with advanced cancer that has not improved with standard treatments. The drug aims to boost your immune system to fight the cancer more effectively.

Guangzhou, Guangdong
NCT07730190Recruiting· Phase 1
Study of TQB6426 for advanced solid tumors

This study tests an investigational drug called TQB6426 for people with advanced solid tumors that have not responded to standard treatments. The drug targets a protein called GPC3 found on some tumor cells. The goal is to see if the drug is safe and effective.

Hefei, Anhui
NCT07043751Recruiting· Phase 1
TQB6411 for advanced solid tumors

This trial tests a new drug, TQB6411, for people with advanced cancers that have not responded to standard treatments. It aims to see if the drug is safe and effective for different tumor types.

Beijing, Beijing Municipality

Hear when a new Cutaneous Squamous Cell Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.