Targeted training to improve walking in Parkinson’s disease
Part of Brain & nervous system clinical trials.
This study tests a targeted motor training approach to improve walking (gait) in people with Parkinson’s disease. You may be considered if your walking is affected but you can already walk steadily for 10 minutes without help.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Parkinson’s disease without a known cause (idiopathic) and your stage is mild to moderate (Hoehn and Yahr 2–3).
- You can walk continuously for 10 minutes on a treadmill and outdoors/overground, without a therapist assisting you.
- Your usual walking speed is between 0.4 and 1.2 meters per second (comfortably in that range).
- Your Parkinson’s rating on the walking-related/leg movement item is at least 1 but less than 3, and you have clear gait continuity problems (like shuffling, freezing, or short steps).
- Your thinking and memory screening is normal for the study (MoCA score 26 or higher).
- You must be able to safely have an MRI (no MRI metal implants and you’re not unable due to claustrophobia).
- You are 50–80 years old and are taking a stable dose of levodopa by mouth; you are not currently doing physical therapy for your walking.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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