Clin2
NCT05865535Possibly a fitRecruiting

Dose study of AV-380 for cancer-related weight loss

Cachexia

Part of Cancer clinical trials.

This Phase 1 trial tests a new drug (AV-380) in people with solid tumor cancer who are losing weight and muscle because of cancer. It mainly helps researchers find a safe dose and see how the body responds, and it may offer a new option for cancer-related cachexia.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Be 18 years or older when you sign consent
  • Have confirmed solid tumor cancer and be on standard treatment (SoC)
  • Meet study criteria for cancer-related cachexia (not just eating less)
  • Expect to live at least 3 months
  • Have no known severe allergy to monoclonal antibody medicines
  • Brain metastases/brain covering disease must be treated and stable for at least 2 weeks, if you have them

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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