Clin2
NCT05866471Possibly a fitRecruiting

Testing nerve stimulation plus psilocybin for emotional well-being

HealthyPsychedelic ExperiencesVagus Nerve Stimulation

Treatments studied

This early safety study tests whether stimulating a nerve (taVNS) combined with psilocybin can change emotional well-being. It also checks safety issues like heart rhythms, lab results, and whether fMRI brain scans are possible.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
108 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You can speak and understand English for study visits and questions
  • You are generally healthy and can complete all study activities
  • Your emotional well-being is somewhat reduced, not fully well
  • Your blood pressure, heart rate, and ECG (heart tracing) are within the study’s safe ranges
  • If you can become pregnant (or are sexually active with someone who can), you can use approved birth control
  • You can do fMRI brain scans and avoid tobacco for at least 12 hours before them

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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