Testing nerve stimulation plus psilocybin for emotional well-being
Treatments studied
This early safety study tests whether stimulating a nerve (taVNS) combined with psilocybin can change emotional well-being. It also checks safety issues like heart rhythms, lab results, and whether fMRI brain scans are possible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can speak and understand English for study visits and questions
- You are generally healthy and can complete all study activities
- Your emotional well-being is somewhat reduced, not fully well
- Your blood pressure, heart rate, and ECG (heart tracing) are within the study’s safe ranges
- If you can become pregnant (or are sexually active with someone who can), you can use approved birth control
- You can do fMRI brain scans and avoid tobacco for at least 12 hours before them
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether taking pimavanserin before psilocybin changes the drug's effects in healthy volunteers who have never used psychedelics. It aims to understand how to make psychedelic therapy safer and more predictable.
This study tests if a mild electrical pulse on the ear (vagus nerve stimulation) can improve thinking and memory in healthy young people. It also looks at whether men and women respond differently.
This Phase 1/2 study tests psilocybin to see how it affects brain signals and the “content” of thoughts while you are monitored during the study. Because participants must be generally healthy and mentally stable, it may be an option if you meet those safety and medication rules and are comfortable having your brain activity measured.
This trial tests whether psilocybin can help people with major depression who are currently having a depressive episode. It aims to understand how the treatment works and if it is safe and effective.
This study tests if a non-invasive device that gently stimulates a nerve in the neck can help reduce PTSD symptoms. You'll receive the stimulation during sessions and share your feedback.
This study tests whether electromagnetic brain stimulation and a psychedelic drug called psilocybin can help people with depression or PTSD. It aims to see how these treatments affect mood and behavior, and whether they are safe and helpful.
Hear when a new Psychedelic Experiences trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.