Study of targeted radiation for rare cancers with limited spread
Part of Cancer clinical trials.
This observational study follows people with rare solid tumors and a limited number of metastases treated with a focused radiation technique (SBRT). Doctors want to see outcomes after using a strong, curative-intent radiation dose to all active spots.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can be up to slightly limited in daily function (ECOG 0–2).
- Your cancer is a rare solid tumor type confirmed by pathology (biopsy/surgery), such as melanoma, sarcoma, head-and-neck, gynecologic tumors, Merkel cell, thymic carcinoma, GIST, or urothelial cancer.
- Your scans show limited-spread disease (oligometastatic/oligorecurrent/oligoprogressive). All active lesions you have must be treated with curative intent.
- The plan must include SBRT to each active spot with an ablative dose at least 50Gy (EQD2) given in up to 10 sessions.
- You have not had radiation to the same metastatic spot before, and you can sign informed consent.
- Your doctors do not consider SBRT unsafe for you (no SBRT contraindications).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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