Clin2
NCT05904964Possibly a fitRecruiting

Targeted drug for hormone-positive, HER2-low metastatic breast cancer

HR Positive/HER2 Low Expression Metastatic Breast Cancer

Treatments studied

Part of Cancer, Skin clinical trials.

This Phase 3 trial tests disitamab vedotin (a targeted drug) in people with hormone receptor–positive, HER2-low metastatic breast cancer that can’t be cured with surgery or radiation. It aims to see whether the drug can control the cancer better than current standard care.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
288 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are an adult (age 18–70) and are female with metastatic breast cancer
  • Your tumor tests show ER and/or PR are positive, and HER2 is “low”
  • Your cancer can’t be cured with surgery or radiation, and you have measurable disease or bone-only lytic metastases
  • You’ve already received endocrine (hormone) therapy, and you’re currently well enough for treatment
  • Recent blood, liver, kidney, and heart test results are within allowed limits
  • You have no recent major chemotherapy/radiation/immunotherapy and no major surgery right before starting

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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