Clin2
NCT07490990Possibly a fitNot yet recruiting

A new drug combination for HER2-positive advanced stomach cancer

HER2-positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

Part of Cancer, Digestive system clinical trials.

This trial tests a combination of two targeted drugs (disitamab vedotin and sintilimab) along with radiation for HER2-positive stomach cancer that has stopped responding to standard treatments. The goal is to see if this combo can shrink tumors and help you live longer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have advanced stomach cancer that tested positive for HER2 (a protein that helps cancer grow).
  • You have tried and failed or couldn't tolerate at least two standard treatments.
  • Your liver is working well enough (Child-Pugh class A).
  • You have at least one tumor that can be measured on a scan, and at least two spots that can get radiation.
  • If you have hepatitis B, it must be well controlled with medication.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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