Breathing carbon dioxide may help low blood pressure symptoms
Part of Brain & nervous system clinical trials.
This proof-of-concept pilot study tests whether a controlled breathing test that re-breathes carbon dioxide can improve symptoms or body responses in people with neurogenic orthostatic hypotension (a drop in blood pressure when standing). It may help researchers understand how the nervous system involved in blood pressure control works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Have a physician diagnosis of neurogenic orthostatic hypotension
- Be a non-smoker
- Be able and willing to sign informed consent
- Be able to travel to the University of Calgary (Libin Cardiovascular Institute Autonomic Testing Lab)
- Be able to follow the study steps and attend visits (they want good compliance)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether breathing in a carefully controlled amount of carbon dioxide (a gas we naturally exhale) can help raise blood pressure in people who get dizzy or faint when standing due to nerve-related blood pressure problems. It could lead to a simple, non-drug way to manage this condition.
This study checks how your body controls breathing and heart rate when you stand up, especially if you get dizzy from low blood pressure. It may help researchers understand what causes symptoms and how to improve testing for people with this condition.
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
This study uses an accelerometer (a wearable motion sensor) to measure symptoms and blood pressure changes when you stand up. It may help doctors better track how neurogenic orthostatic hypotension affects you and how well current treatments are working.
This study measures how breathing patterns and heart rate/blood pressure change when you move from lying to standing in people with POTS. It may help researchers understand symptoms better and improve ways to manage them.
This trial looks at how blood pressure and heart rate change when standing up or exercising in healthy people and in older adults with high blood pressure. It aims to understand how the body's automatic (autonomic) nervous system controls these functions.
Hear when a new Neurogenic Orthostatic Hypotension trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.