Wearable sensor study for low blood pressure on standing
Part of Brain & nervous system, Heart & circulation clinical trials.
This study uses an accelerometer (a wearable motion sensor) to measure symptoms and blood pressure changes when you stand up. It may help doctors better track how neurogenic orthostatic hypotension affects you and how well current treatments are working.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 40 to 80 years old
- You have possible or probable multiple system atrophy, pure autonomic failure, or Parkinson’s disease with low blood pressure on standing
- When you stand, your top blood pressure (systolic) drops by at least 30 points within 3 minutes, and there’s no other clear cause
- You’re taking midodrine or atomoxetine, and your symptoms are still present but not severe (OHSA score 1 to 5)
- You can walk and are able to stay with a caregiver during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
This study follows people over time to better understand “synucleinopathies,” which are conditions that affect the nervous system as it develops and progresses. You may be asked to return for visits and report symptoms, especially those that happen when you stand up.
This proof-of-concept pilot study tests whether a controlled breathing test that re-breathes carbon dioxide can improve symptoms or body responses in people with neurogenic orthostatic hypotension (a drop in blood pressure when standing). It may help researchers understand how the nervous system involved in blood pressure control works.
This trial looks at how blood pressure and heart rate change when standing up or exercising in healthy people and in older adults with high blood pressure. It aims to understand how the body's automatic (autonomic) nervous system controls these functions.
This trial tests a new intelligent diagnostic system to help diagnose orthostatic hypotension (a drop in blood pressure when standing up) in people with Parkinson's disease, multiple system atrophy, or diabetes. It uses a non-invasive ultrasound device (TCD) to monitor blood flow in the brain.
This study checks how your body controls breathing and heart rate when you stand up, especially if you get dizzy from low blood pressure. It may help researchers understand what causes symptoms and how to improve testing for people with this condition.
Hear when a new Autonomic Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.