Testing heart pump unloading during VA ECMO in adults
Part of Heart & circulation clinical trials.
This study will look at whether “left ventricular unloading” (using a device like IABP or Impella) helps people who are in cardiogenic shock while on VA ECMO. It compares outcomes for people who get unloading versus those who stay on VA ECMO alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older
- You have been treated with VA ECMO for severe circulation and/or breathing problems
- You have cardiogenic shock
- A left-heart unloading device (IABP or Impella) could be started within 8 hours of starting ECMO
- You (or your medical decision-maker) agree to join the study registry and consent to the trial
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if unloading the heart during ECMO support helps patients recover better from cardiogenic shock. It compares different ways to reduce the heart's workload.
This study is a registry that collects information from adults who need a temporary heart circulation support device such as VA-ECMO or an Impella pump (or newer similar devices). It may help doctors better understand which patients benefit most and how these devices are used in real life.
This trial looks at a “precision” strategy for people in severe heart-related shock who are starting VA ECMO (a life-support machine). It will be done through a hospital registry system, which helps doctors learn which patients benefit most and why.
This study compares two support devices (Impella vs. IABP) for people with cardiogenic shock who are already on ECMO. It looks at how well the left side of the heart recovers when one of these devices is added.
This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
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