Social reward therapy for depression-related suicidal thoughts
Part of Mental health clinical trials.
This study looks at whether “social reward” psychotherapy can change brain activity and reduce suicidal thoughts in adults ages 50–80 who also have major depression. You may be offered psychotherapy along with brain scans to see how your brain responds over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 50 and 80 years old
- Have current suicidal thoughts at a level the study checks with a structured interview
- Be diagnosed with major depression, confirmed by the same structured interview
- Have a depression score on a standard rating form of 16 or higher
- Be able to do MRI brain scans (no MRI-blocking implants and you’re not too claustrophobic)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new type of brain stimulation called temporal interference stimulation to see if it can improve how people with depression experience social rewards. You may be eligible if you have depression with certain features like increased appetite, weight gain, or feeling very sensitive to rejection, and you are between 16 and 60 years old.
This study tests whether stimulating the brain on both sides at once versus one side can reduce suicidal thoughts in people with treatment-resistant depression. It also looks at brain “inhibition” signals to help predict who benefits.
This study looks at how certain brain “inhibitory” signals work in teenagers and young adults who have depression and either suicide thoughts or past suicide behavior. The goal is to better understand suicide risk and what might help reduce it, using brain and brainwave testing.
This study tests a new type of brain stimulation called TMS (transcranial magnetic stimulation) for young people ages 15-25 who are having serious depression and suicidal thoughts. The goal is to see if this treatment can help reduce risk and improve mood.
This study looks at how your brain works during talk therapy for depression. It aims to find out how therapy helps you feel better so that future treatments can be more personalized.
This study uses brain scans (MRI) to understand how people with depression process rewards, aiming to identify different depression subtypes. You may join if you have depression or if you are a healthy volunteer.
Hear when a new Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.