Brain stimulation type test for suicidal thoughts in depression
Part of Mental health clinical trials.
This study tests whether stimulating the brain on both sides at once versus one side can reduce suicidal thoughts in people with treatment-resistant depression. It also looks at brain “inhibition” signals to help predict who benefits.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have a current major depressive episode, and your depression rating is high enough (HRSD 18 or more).
- You still have suicidal thoughts beyond the initial screening, with a score of 4 or higher on the Beck Suicidal Ideation scale.
- You can pass study safety checks for TMS (brain stimulation) and MRI (brain scan) and you can safely have an MRI.
- Your depression has not responded to at least two antidepressant tries in this current episode (either not effective at a proper dose, or not tolerated).
- You must be able to consent and attend the outpatient treatment visits on schedule.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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