First treatment ablation for early persistent irregular heartbeats
Part of Heart & circulation clinical trials.
This Phase 3 trial tests whether doing a heart rhythm procedure (cryoablation) early can control persistent atrial fibrillation (AF) better than usual treatment. It’s meant for people who have ongoing symptoms and are good candidates for rhythm-control therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have non-longstanding persistent AF with symptoms, with at least two AF episodes in the last 24 months; the most recent was within 6 months
- Your latest AF episode is confirmed by a 12-lead ECG or a Holter monitor
- Your AF type is either “classical persistent” (continuous for more than 7 days but under 12 months) or persistent AF that developed from paroxysmal AF
- You’re a candidate for rhythm-control treatment (either AF ablation or antiarrhythmic medicines)
- You have NOT had prior AF ablation or heart surgery for AF
- You do not have major heart or lung conditions that make ablation unsafe (for example: severe heart failure, very weak pumping, severe valve disease, severe COPD, or severe kidney disease)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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