Testing genes in severe language and learning difficulties
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study uses a special DNA test (trio exome sequencing) on a child or young adult and their two biological parents to look for a genetic cause of language and learning difficulties. If a genetic reason is found, it may help explain the cause and guide future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your child) are 3 to 40 years old and have severe language and/or learning problems needing extra in-school help or intensive therapy.
- You have not had genetic testing like this yet (no previous trio exome testing/array CGH/Fragile X/other targeted genetic tests, except a standard chromosome test).
- If needed, your learning/language problems should be supported by specialist assessments (neuropsychology, speech therapy, and/or occupational therapy) reviewed by experts.
- The study can take a DNA sample from you and both biological parents (or those parents must be available for testing).
- Parents must agree, and if you are an adult you must also sign consent; you also must have coverage under national health insurance.
- The study may not include cases where there is likely an intellectual disability confirmed/suspected, an obvious syndrome causing development issues, pregnancy/breastfeeding, or certain living/safety situations.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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