Clin2
NCT05949606Possibly a fitActive, not recruiting

New study for advanced lung cancer using two antibody drugs

Non-small Cell Lung Cancer

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This Phase 1/2 trial tests whether two antibody drugs (SI-B001 and SI-B003) work well for locally advanced or metastatic non-small cell lung cancer, sometimes together with chemotherapy. It may help shrink tumors and control the disease, while closely monitoring safety and side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
95 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • Be 18 to 75 years old, and able to estimate at least 3 months of life expectancy
  • Have confirmed locally advanced or metastatic non-small cell lung cancer (NSCLC)
  • Have at least one tumor spot doctors can measure on scans
  • Be well enough for treatment (ECOG performance status 0 to 1)
  • Be able to provide tumor tissue (fresh or stored) and do ctDNA testing during screening
  • Have recovered from past cancer treatment side effects to mild levels (no worse than Grade 1)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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