Guanfacine for teens with cannabis use problems
Part of Mental health clinical trials.
This Phase 2 study tests whether extended-release guanfacine can reduce cannabis use in adolescents and young adults. It may help by targeting brain pathways that can drive cravings or continued use.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 12 to 25 when you sign consent
- You are looking for help with cannabis (marijuana) use
- A clinician diagnoses you with cannabis use disorder (mild, moderate, or severe)
- In the last 28 days, you used cannabis at least 5 days per week, and your urine test is THC-positive on screening day
- You can give consent/assent in English (and have an IQ level that allows consent); if you are under 18, a parent/guardian also consents
- You are not currently being treated with certain meds (especially sedatives/antipsychotics), and any antidepressant use has been stable for over 2 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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