Clin2
NCT05962463Possibly a fitRecruiting

Compare two pain injections for advanced knee arthritis

Knee Osteoarthritis

Part of Bones, joints & muscles clinical trials.

This trial compares pulsed radiofrequency therapy versus a targeted nerve pain block to help reduce knee pain from advanced osteoarthritis. You might join if you have knee osteoarthritis in the more severe range (Kellgren-Lawrence grade 3–4) and meet safety requirements.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
128 people
Ages
45 years to 100 years
Study type
Observational

Who can take part

  • You’re over 45 years old
  • A doctor has confirmed knee osteoarthritis on exam
  • Your knee arthritis is in the severe range (K-L grade 3 or 4)
  • You can understand and communicate about study visits and instructions
  • You must not have serious heart, liver, or kidney problems that could affect participation
  • You must not have allergies to any study medicines or procedures

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06798038Not yet recruiting· Phase 1
Comparing nerve-blocking treatments for knee arthritis pain

This study compares three minimally invasive treatments to reduce knee pain from osteoarthritis. These treatments aim to block the nerves around the knee using alcohol injection, phenol injection, or a technique that uses heat to disable the nerves.

NCT07868770Not yet recruiting
Ultrasound-guided knee block for osteoarthritis pain

This study tests whether a nerve block around the knee, guided by ultrasound, can reduce pain in people with moderate knee osteoarthritis. It may offer a new way to manage pain without surgery.

Ankara
NCT06166628Recruiting
Comparing two procedures for knee osteoarthritis pain

This study compares two minimally invasive procedures—embolization (blocking blood flow) and nerve ablation (blocking pain signals)—to see which works better for knee osteoarthritis pain. If you have long-lasting knee pain and are considering knee replacement surgery, this trial may help find another option.

Kingston, Ontario
NCT07789340Recruiting
Radiofrequency treatment for knee osteoarthritis pain

This study compares two types of radiofrequency treatment to reduce knee pain from osteoarthritis. It may help people whose knee pain has not improved with other treatments like physical therapy or injections.

Tanta, El-Gharbia
NCT07853170Recruiting
Comparing 3 vs 5-needle knee nerve blocks for arthritis pain

This study compares two ways of numbing the nerves around the knee to see which gives better pain relief and improves quality of life for people with knee osteoarthritis. It might help you decide if a nerve block is a good option for your knee pain.

Tanta, El-Gharbia
NCT07703293Recruiting
Testing nerve branches for chronic knee pain relief

This study tests a procedure targeting specific nerve branches in the thigh to treat long-lasting knee pain from osteoarthritis. It may help people who haven't found relief from standard treatments like pain relievers or physical therapy.

Ankara

Hear when a new Knee Osteoarthritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.