Study of a patient’s own CAR T cells for CD19 cancers
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This Phase 1 study tests a personalized form of CAR T cell treatment made from your own immune cells to fight certain CD19-positive blood cancers that have returned or not responded to prior treatment. It mainly looks at safety and how well the treatment can work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed CD19-positive blood cancer: lymphoma (NHL), CLL, or SLL, and you’ve had at least 2 prior treatments
- You are 18 or older, and your overall health is good enough for study treatment (ECOG 0 or 1)
- You should have an expected lifespan of more than 4 months
- Your heart, lungs, liver, kidneys, and bone marrow must be healthy enough for treatment
- You must not have had certain immune conditions or infections (including active TB, HIV, active hepatitis B/C, or active HTLV/syphilis)
- You must not have had prior CD19-targeted therapy, a recent transplant using anti-rejection medicines, or live vaccines close to cell collection
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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