SGLT2 drug trial for belly fat inflammation before weight-loss surgery
Treatments studied
Part of Hormones & metabolism clinical trials.
This early-phase trial tests whether an SGLT2 drug can reduce inflammation in belly fat and improve blood vessel function. It may help people with metabolic syndrome prepare for (and potentially benefit around) planned gastric bypass or sleeve surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 years or older
- You have metabolic syndrome (you meet 3+ of these: high blood pressure, high triglycerides, low HDL, high fasting sugar, or large waist)
- Your BMI is 35 or higher
- You have gastric bypass or gastric sleeve surgery planned in about 90–270 days
- You have stable diabetes medicines: metformin or a sulfonylurea (and only if used at a stable dose for the last month)
- You’re not on certain other diabetes or recent SGLT2/GLP-1 medicines (see questions below)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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