Using fecal transplant to clear antibiotic-resistant bacteria
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial tests whether giving healthy bacteria through capsules (a fecal transplant) can help get rid of CRE, a type of bacteria that is hard to treat because it resists many antibiotics. If successful, this could reduce the risk of serious infections.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older
- You must be currently admitted to a hospital medical ward
- You must have tested positive for CRE (a type of antibiotic-resistant bacteria) in a rectal swab or stool sample within the past week
- You cannot be pregnant
- You cannot have taken antibiotics in the 30 days before the study starts
- You must be able to swallow capsules without difficulty
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 3 study tests whether a fecal microbiota transplant (FMT) can eliminate hard-to-treat bacteria in the gut, such as ESBL or carbapenem-resistant bacteria. If it works, it may reduce future infections and antibiotic-resistant illness.
This trial tests whether a fecal transplant can remove multidrug-resistant bacteria from the gut, potentially reducing the risk of infections. It may help patients who carry these bacteria without symptoms.
This trial tests whether taking capsules containing processed healthy donor stool (fecal microbiota transplant) can safely remove certain drug-resistant bacteria (like CRE, ESBL-E, and VRE) from your intestines. It may be an option for people who have these bacteria in their stool but are not currently being treated with antibiotics.
This study tests whether a fecal transplant (FMT) can remove certain antibiotic-resistant bacteria from your gut. It might help people who carry superbugs like CPE or VRE but aren't currently on antibiotics.
This study tests a stool-based treatment (fecal microbiota treatment) to help remove “carbapenem-resistant” bacteria living in the gut. If you carry these bacteria without being sick, the goal is to reduce or stop that colonization.
This trial looks at a treatment made from stool donors (called fecal microbiome therapy) to help remove carbapenem-resistant gut bacteria in the body. It’s mainly for adults who recently tested positive for these bacteria on a rectal swab, and it checks whether the therapy can help eradicate the germs.
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