Fecal transplant to clear resistant gut bacteria
Part of Infections clinical trials.
This Phase 3 study tests whether a fecal microbiota transplant (FMT) can eliminate hard-to-treat bacteria in the gut, such as ESBL or carbapenem-resistant bacteria. If it works, it may reduce future infections and antibiotic-resistant illness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to under 105 years old
- You have proof from a rectal swab or recent test of resistant gut bacteria (ESBL-E or CRE), or a recent ESBL-E/CRE infection in the last year (for ESBL carriers, that recent infection is required)
- If you are assigned to take treatment by mouth, you must be able to swallow 50 capsules in a day with no swallowing problems
- You cannot currently be on antibiotics, except long-term antibiotic prevention (at least 3 months in a year)
- You must not be in the intensive care unit (ICU), and you must not be pregnant or breastfeeding
- You must be able to follow study rules (birth control if needed, no other treatment trials, and consent to participate)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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