Dapagliflozin with chemo for breast cancer
Treatments studied
Part of Cancer, Hormones & metabolism, Skin clinical trials.
This trial tests whether adding the drug dapagliflozin (a pill that lowers blood sugar) to standard chemotherapy before breast cancer surgery can improve outcomes. It is for women with high insulin levels and a higher BMI who are about to start chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman over 18 with newly diagnosed breast cancer that is either ER-positive or triple-negative (HER2-negative).
- Your body mass index (BMI) is 25 or higher.
- You have high fasting insulin levels, a sign of insulin resistance.
- You are scheduled to receive chemotherapy before surgery (neoadjuvant therapy).
- You are not pregnant or breastfeeding, and you do not have diabetes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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