Clin2
NCT05990790Possibly a fitRecruiting

Comparing anesthetics and their effect on confusion after surgery

Postoperative DeliriumMajor Noncardiac SurgeryPostoperative Cognitive Dysfunction

Treatments studied

Part of Brain & nervous system, Mental health clinical trials.

This study compares three different anesthesia medicines to see which one might lower the chance of confusion or delirium after major surgery. If you are 65 or older and having a long, planned non-heart surgery, this trial could help determine the safest option for you.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
1,332 people
Ages
65 years and older
Study type
Interventional

Who can take part

  • You are 65 years old or older
  • You are scheduled for a planned major surgery (not an emergency) that is expected to last at least 2 hours
  • The surgery is not on your heart
  • You do not have a history of dementia or memory problems
  • You do not have a history of malignant hyperthermia (a rare reaction to anesthesia)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04707794Recruiting
Preventing confusion after non-heart surgery in older adults

This study looks at how often older adults develop sudden confusion (delirium) after non-heart operations under general anesthesia. It may help doctors better predict who is at risk and improve care after surgery.

New Delhi, National Capital Territory of Delhi
NCT07612579Recruiting
Anesthesia choice and delirium after surgery

This study compares two types of anesthesia (propofol and sevoflurane) to see which one helps prevent confusion and delirium after surgery. Delirium is a temporary state of confusion that can happen after surgery, and researchers want to understand which anesthesia approach might reduce this risk.

Berlin
NCT06423547Recruiting
Predicting confusion after surgery in older adults

This study looks at older patients (65 and older) who have had surgery and anesthesia. It aims to find who is at risk for confusion (delirium) and memory problems afterward. The goal is to help doctors prevent these issues.

Beijing
NCT07192549Not yet recruiting
Predicting confusion after surgery in young children

This study looks at whether a protein called GDNF in the blood can help predict if a child will become confused or have other brain problems after surgery. It aims to improve how we care for children during and after their operation.

NCT06036095Recruiting· Phase 4
Comparing two types of anesthesia in older adults having surgery

This study compares two types of general anesthesia for older adults (70+) having planned non-heart, non-brain surgery that lasts at least 2 hours. The goal is to see which type might be better for preserving thinking and memory after surgery.

Portland, Oregon
NCT07799623Not yet recruiting
Anesthesia choice and confusion after brain tumor surgery

This study tests whether three different anesthesia medicines (ciprofol, propofol, and sevoflurane) might reduce confusion or disorientation after brain tumor surgery in older adults. Participants will be randomly assigned to receive one of these anesthetics, and their recovery will be monitored.

Wuhan, Hubei

Hear when a new Postoperative Delirium trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.